Mechanism of action of neuroleptics

Laborit in the early 1950s is credited with the observation that chlorpromazine had a ''calming'' effect in disturbed schizophrenic patients and since that time psychopharmacologists have sought to explain the mechanism of action of neuroleptic drugs. Carlsson and Linquist in 1963 demonstrated a link between the therapeutic effects of the phenothiazine neuroleptics and an inhibition of dopamine receptor function. This led to

Table 11.4. New families of dopamine receptor subtypes

Family

Relevance for antipsychotic drug action

Was this article helpful?

0 0
Diet And Exercise Expertise

Diet And Exercise Expertise

Get All The Support And Guidance You Need To Be A Success At Dieting And Exercise. This Book Is One Of The Most Valuable Resources In The World When It Comes To Better Physical Personal Development Through Better Living.

Get My Free Ebook


Post a comment