Adenocarcinomas account for less than 15% of esophageal cancers, but their incidence is rising sharply. They may arise from ectopic gastric mucosa or columnar-lined esophagus, or they may result from the contiguous spread of a cardia malignancy.
Endoscopic diagnostic criteria (Figs. 3.66, 3.67)
► Highly variable endoscopic appearance
- Superficial mucosal alteration, discoloration
- Nodular or depressed mucosa
- Erythema, erosion, or ulceration
- Mucosa is friable, bleeds easily on examination and biopsy
- Exophytic, polypoid mass (most common form)
- Fungiform, clefted surface, sometimes with central excavation
- Erythema, erosion, ulceration
- Pale gray, sometimes reddish discoloration
- May be sharply or poorly demarcated from the surrounding mucosa
► Biopsy with generous margins
► Radiographic contrast examination
► Usual staging work-up
Was this article helpful?