Rigorous review by research ethics committees can:
• provide a powerful preventative measure in tackling research misconduct;
• provide a culture in which it is more difficult for research misconduct to flourish;
• help prevent less good research practice and protect patients and the public against harm from research and researchers;
• encourage a culture in which good quality, well-justified, well-planned, and appropriately designed biomedical research can flourish;
• facilitate ethically acceptable attempts to identify new and better treatments from which all may potentially benefit.
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