How Human Embryonic Stem Cell Research Can Impact InVitro Drug Screening Technologies of the Future 205

André Schrattenholz and Martina Klemm

8.1 Introduction 205

8.2 First Excursion: Protein Surrogate Biomarker Signatures 208

8.3 Second Excursion: Validation 211

8.4 Reproductive Toxicology and In-Vitro Tests 213

8.5 Reproductive Toxicology and hESC 214

8.6 Efficacy and Mode of Action Studies:

Systems Biology Using Embryonic Stem Cell-Based Screening Systems 218

8.7 Conclusions and Outlook 221 References 222

0 0

Post a comment