Children without Recognizable Pathology

Obese prepubertal children are relatively tall for age (many in the upper quartile and most in the upper half of the population distribution for height). Advanced growth may be associated with advanced maturity of bones (advanced bone age), early onset of puberty, and cessation of growth with only average stature in adult life. However, some children remain tall and obese into adult life, and others slim dramatically with the adolescent growth spurt. It is not clear whether obesity drives accelerated maturation or whether obesity is one manifestation of a predisposition to exuberant growth of both lean and fat tissue also expressed by early puberty.

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