Classification of Hyperlipidemia

There are a number of classification systems available. In 1967, Fredrickson, Levy, and Lees introduced the first classification as a method of reporting that lipoproteins were raised. The World Health Organization adopted this classification (Table 3).

In 1987, the European Atherosclerosis Society recommended a five-group classification of primary hyperlipidemia (Table 4), and the National Cholesterol Education Program Adult Treatment Panel III published guidelines in 2002 for normal and elevated lipid levels (Table 5).

Clinically, the most important step is to determine if the lipid abnormality is primary or secondary to another condition. Table 6 shows the lipid changes seen in some common conditions. In practice, it is often easiest to classify lipid abnormalities into three

Table S Fredrickson/WHO classification of hyperlipoproteinemia


Lipids increased

Lipoprotein increased

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