Classification of Serum Lipoproteins According to Their Apolipoprotein Composition

Recent interest on the study of lipoprotein subfractions has resulted in an increased use of methods of separation based on affinity chromatography, specially those using immunoaffinity. By using columns containing antibodies against specific apolipopro-teins (Table 2), a large number of HDL subpopulations have been resolved. Similarly, this technique

Table 2 Classification and properties of apolipoproteins

Apolipoprotein Amino acids Tissue expression Chromosomal localization Functions apo A-I

apo A-II apo A-IV

apo B-48

apo B-100 apo C-I

apo C-II

apo C-III

apo D

apo E

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