Co2

Figure 4 Ion movements in HCL secretion. Thick arrows at top show apical recycling of K+. ||, ion channel; O, anion exchanger;

cation exchanger; CA, carbonic anhydrase. Na+ may be transported instead of H3O+. HCO3 transport back into the blood during acid secretion is the so-called 'alkaline tide.' Cl3 entry via the basolateral membrane may be linked to Na+ entry. Cl3 exiting across the apical membrane into the lumen may be linked to K+ efflux.

Apical membrane

Parietal cell

Basolateral membrane

HCO-Blood

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