Myopathy is common, affecting up to two-thirds of all alcoholics. It is characterized by wasting, weakness, and myalgia and improves with abstinence. Histology correlates with symptoms and shows selective atrophy of type II muscle fibers. Ethanol causes a reduction in muscle protein and ribonucleic acid content. The underlying mechanism is unclear, but rates of muscle protein synthesis are reduced, whereas protein degradation is either unaffected or inhibited. Attention has focused on the role of acetaldehyde adducts and free radicals in the pathogenesis of alcoholic myopathy.
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Alcoholism is something that can't be formed in easy terms. Alcoholism as a whole refers to the circumstance whereby there's an obsession in man to keep ingesting beverages with alcohol content which is injurious to health. The circumstance of alcoholism doesn't let the person addicted have any command over ingestion despite being cognizant of the damaging consequences ensuing from it.