Enteral Branched Chain Amino Acid Formulations

Patients with hepatic encephalopathy have low levels of enteral branched-chain amino acids (BCAAs) and increased levels of phenylalanine and tryptophane. It has been postulated that since BCAAs compete with phenylalanine and trypto-phane for transport through the blood-brain barrier, reduced levels of BCAAs promote the accumulation of these amino acids in the brain, where they are metabolized to false neurotransmitters that then cause encephalopathy. To reverse this state, BCAA-enriched formulas were developed, and in a meta-analysis of randomized controlled trials of these formulations in hepatic encephalopathy, they were shown to reduce the duration of encephalopathy in comatose patients.

Was this article helpful?

0 0
Food Allergies

Food Allergies

Peanuts can leave you breathless. Cat dander can lead to itchy eyes, a stuffy nose, coughing and sneezing. And most of us have suffered through those seasonal allergies with horrible pollen counts. Learn more...

Get My Free Ebook


Post a comment