Further Reading

Berry RJ, Li Z, Erickson JD et al. for the China-U.S. Collaborative Project for Neural Tube Defect Prevention (1999) Prevention of neural tube defects with folic acid in China. New England Journal of Medicine 341: 1485-1490. Botto LD and Yang Q (2000) 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGe review. American Journal of Epidemiology 151: 862-877. Botto LD, Moore CA, Khoury MJ, and Erickson JD (1999) Neural-tube defects. New England Journal of Medicine 341: 1509-1519.

Centers for Disease Control and Prevention (1991) Use of folic acid for prevention of spina bifida and other neural tube defects—1983-1991. Morbidity and Mortality Weekly Report 40: 513-516.

Centers for Disease Control and Prevention (1993) Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. Morbidity and Mortality Weekly Report 41(RR-14): 1-7. Committee on Medical Aspects of Food and Nutrition Policy (2000) Folic Acid and the Prevention of Disease. London: Department of Health. Daly LE, Kirke PN, Molloy A, Weir DG, and Scott JM (1995) Folate levels and neural tube defects—Implications and prevention. Journal of the American Medical Association 274: 1698-1702.

Daly S, Mills JL, Molloy AM et al. (1997) Minimum effective dose of folic acid for food fortification to prevent neural tube defects. Lancet 350: 1666-1669. Elwood JM, Little J, and Elwood JH (1992) Epidemiology and Control of Neural Tube Defects. Oxford: Oxford University Press. EUROCAT Working Group (2003) EUROCAT Special Report: Prevention of Neural Tube Defects by Periconceptional Folic Acid Supplementation in Europe. Belfast: University of Ulster. Available at www.eurocat.ulster.ac.uk/pubdata/folic%20acid.html. Expert Advisory Group (1992) Folic Acid and the Prevention of

Neural Tube Defects. London: Department of Health. Scott JM, Kirke PN, and Weir DG (1995) Folate and neural tube defects. In: Bailey L (ed.) Folate in Health and Disease, pp. 329-360. New York: Marcel Dekker. Shields DC, Kirke PN, Mills JL et al. (1999) The "thermolabile" variant of ethylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother. American Journal of Human Genetics 64: 1045-1055. Wald NJ, Hackshaw AK, Stone R, and Sourial NA (1996) Blood folic acid and vitamin B12 in relation to neural tube defects. British Journal of Obstetrics and Gynaecology 103: 319-324.

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