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aEthanol appears in the blood as quickly as 5 minutes after ingestion and is rapidly distributed around the body. A dose of 0.8 g ethanol/kg body weight (56 g ethanol (7 units) consumed by a 70 kg male) should result in a blood ethanol concentration of 100-200 mg/dl (22-43 mmol/l) between 15 and 120 minutes after dosage. Highest concentrations occur after 30-90 minutes.

aEthanol appears in the blood as quickly as 5 minutes after ingestion and is rapidly distributed around the body. A dose of 0.8 g ethanol/kg body weight (56 g ethanol (7 units) consumed by a 70 kg male) should result in a blood ethanol concentration of 100-200 mg/dl (22-43 mmol/l) between 15 and 120 minutes after dosage. Highest concentrations occur after 30-90 minutes.

gastric emptying is the main determinant of absorption because most ethanol is absorbed after leaving the stomach through the pylorus.

Alcohol diffuses from the blood into tissues across capillary walls. Ethanol concentration equilibrates between blood and the extracellular fluid within a single pass. However, equilibration between blood water and total tissue water may take several hours, depending on the cross-sectional area of the capillary bed and tissue blood flow.

Ethanol enters most tissues but its solubility in bone and fat is negligible. Therefore, in the postabsorption phase, the volume of distribution of ethanol reflects total body water. Thus, for a given dose, BEC will reflect lean body mass.

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