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aThis cell type circulates as monocytes in the bloodstream and matures into macrophages when taking up residence in a tissue.

Figure 1 Immune cells give rise to either lymphoid or myeloid progenitors, which subsequently differentiate into the different immune cells.

aThis cell type circulates as monocytes in the bloodstream and matures into macrophages when taking up residence in a tissue.

through the bloodstream into the peripheral, or secondary, lymphoid tissues. These include the lymph nodes, spleen, and lymphoid tissues associated with mucosa, and they constitute the main sites at which the reaction of B and T lymphocytes with foreign antigens takes place. Lymph then carries circulating lymphocytes from the peripheral lymphoid tissues to the thoracic duct, where they reenter the bloodstream. The functions of the various immune cells are summarized in Table 1.

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