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Uganda

Preschool and school-aged children

Mid upper arm circumference

aAn improvement with supplemental zinc was observed only when administered simultaneously with other micronutrients.

aAn improvement with supplemental zinc was observed only when administered simultaneously with other micronutrients.

playing as opposed to sitting or watching, have been observed among infants in developing country settings in response to supplemental zinc. Nonetheless, other studies have failed to demonstrate an effect of zinc on motor scores as assessed by Bayley Scales or Griffiths' Developmental Assessment and, in one case, a negative effect on the mental development index was observed.

Evidence for improved cognitive function among school-aged children has been derived from studies of urban and rural children in China. In the rural population of children, the positive effect of zinc on cognitive function was dependent on the provision of other supplemental micronutrients, while in the urban group, supplemental zinc had a positive effect that was independent of the provision of other micronutrients. It is possible that some of the inconsistencies in the studies of neurobehavioral development occur due to concurrent deficiencies of other nutrients that also play a role in cognition (e.g., iodine, iron).

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