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aThe submucosal plexus is an important structure in the human stomach, containing a number of transmitters, e.g., substance P, vasoactive intestinal peptide (VIP), nitric oxide, calcitonin gene-related peptide (CGRP), and gastrin-releasing peptide (GRP).

aThe submucosal plexus is an important structure in the human stomach, containing a number of transmitters, e.g., substance P, vasoactive intestinal peptide (VIP), nitric oxide, calcitonin gene-related peptide (CGRP), and gastrin-releasing peptide (GRP).

extending towards the top. These cells secrete hydrochloric acid (HCl) and intrinsic factor into the gland lumen. Also present near the base of the glands in this region of the stomach are neuroendocrine cells, i.e., enterochromaffin cells secreting

Soluble, degraded mucin

Mucous gel barrier (polymeric mucin)

Mucus-secreting cells migrate up

Lumen secreting neck cells

Mucus-secreting cells migrate up

Acid-secreting cells migrate down

Lumen secreting neck cells

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