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Na+ H2O

1. Na+ is concentrated between cells

2. H2O follows the osmotic gradient. Pressure rises

3. H2O and Na+ move towards base of cell and into blood

Figure 3 Electrolyte transport across the cell membrane and the different types of tranporters. (Reproduced with permission from Guyton (1991) Guyton's Textbook of Medical Physiology, 8th edn. Philadelphia: WB Saunders.)

Figure 3 Electrolyte transport across the cell membrane and the different types of tranporters. (Reproduced with permission from Guyton (1991) Guyton's Textbook of Medical Physiology, 8th edn. Philadelphia: WB Saunders.)

transport processes involving calcium. The electrochemical gradient formed by the activity of these ion channels facilitates the function of smooth muscle action potential generation upon depolarization. With the generation of smooth muscle action potentials attaining threshold voltage, contractility of the smooth muscle is possible. The efflux of calcium into these active transport channels activates the process of contraction. Interaction with the enteric nervous system stimulates the release of calcium ions in intracellular stores. The function of ion channels can be modified by calcium channel-blocking drugs. This contractile activity, when it occurs in a coordinated fashion and is modulated by neurotransmission, effects peristalsis and colonic motility.

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