Info

Removal of potentially harmful peroxides and modulation of eicosanoid synthesis

Type I

Tetramer

>50% of total Se in body; acts as Se buffer/store

Type II

Tetramer

May protect the intestine

Type III

Tetramer

Found in plasma and milk; synthesized in kidney

Type IV

Monomer

Phospholipid hydroperoxide GPx; abundant in testis; resistant to Se deficiency; involved in eicosanoid metabolism

Thioredoxin reductases

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