Intradermal Testing

Intradermal testing comprises the intradermal injection of 0.01-0.05 ml of an allergen extract. It can cause fatal generalized allergic reaction (anaphy-laxis), and is only performed if a preliminary skin prick test is negative. Intradermal tests are more sensitive than skin prick testing, and hence also produce even more false-positive reactions, making the interpretation of the results of intradermal testing even more difficult than that for skin prick testing. The difficulty in interpretation of the results, the pain of intradermal injections, and the risk of anaphylaxis mean that intradermal testing has no place in the routine investigation of food allergy.

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