Vitamin E is the most potent fat-soluble antioxidant in human plasma. Although vitamin E was first discovered in 1922, its metabolic function remains an enigma. There are eight different molecular forms with vitamin E antioxidant activity, yet the body preferentially retains a-tocopherol. This preference for a-tocopherol has led the Food and Nutrition Board in its 2000 Dietary Reference Intakes (DRIs) for vitamin E to recommend that only a-tocopherol, not the other forms, meets human requirements for vitamin E. Moreover, only a-tocopherol is recognized by the hepatic a-tocopherol transfer protein (a-TTP). This protein regulates plasma a-tocopherol concentrations and genetic abnormalities in the protein (or its absence) leads to vitamin E deficiency in humans.

Psychology Of Weight Loss And Management

Psychology Of Weight Loss And Management

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