Fatty acids and glucose are the primary metabolic fuels used by higher organisms, including man. As such, fatty acids occupy a central position in human nutrition. Fat, carbohydrate, and protein comprise the macronutrients. When nutritionists speak of fat, they are referring mainly to triacylgly-cerol (triglyceride), which consists of three fatty-acid molecules covalently linked to a backbone of glycerol. Several properties of fatty acids and tria-cylglycerol make them highly suited to the storage and provision of energy. When a gram of fatty acid is burned as fuel, about 9kcal of energy is recovered - more than twice that yielded when a gram of carbohydrate or protein is utilized. Unlike carbohydrates, fat can be stored in an anhydrous compact state, allowing the organism to amass large quantities of fuel reserves in times of plenty. This property can have unfortunate consequences in prosperous societies, as evidenced by the increasing incidence of obesity. Fatty acids are also fundamental building blocks for the synthesis of most biologically important lipids, including phospholipids, sphingolipids, and cholesterol esters. They are the precursors of bioactive molecules such as prosta-glandins and other eicosanoids. In addition, fatty acids and their coenzyme A derivatives have many metabolic regulatory roles.

The Ketosis Plan Diet

The Ketosis Plan Diet

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