Lipid Emulsions

Glucose was the only nonprotein source of energy until intravenous lipids were developed during the 1920s to the 1960s. The first emulsion available for clinical use was Lipomul, a cottonseed oil-based formulation. Because there were many adverse effects from its use, it was withdrawn from clinical use in the mid-1960s. After extensive testing, Wretlind developed Intralipid, a soybean-based emulsion, in 1961. It was well tolerated and is the most familiar intravenous fat emulsion currently available. It is available in 10, 20, and 30%

Table 2 Pediatric parenteral nutritional requirements
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