Nonmalignant Complications of Celiac Disease

Nonmalignant complications of celiac disease include ulcers and structuring within the intestine that occasionally may present with small bowel obstruction and/or bleeding, and recurrent acute pancreatitis as the result of inflammation, probably of the sphincter of Oddi. Nongastrointestinal complications are usually the consequence of malnutrition or specific deficiencies. However, others such as neurological problems including ataxia, peripheral neuropathy, or dementia are of uncertain mechanism and perhaps autoimmune in nature. Other consequences of celiac disease have been discussed in the section on atypical or nongastrointestinal presentations (Table 1). Many, but not all, of these nonmalignant complications of celiac disease will respond to a gluten-free diet.

See also: Cereal Grains. Cytokines. Handicap: Down's Syndrome. Osteoporosis. Vitamin D: Rickets and Osteomalacia.

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