Nsaid

Food Alcohol

Glucose

Calcium, phosphorus, vitamin D

Nitrogen Zinc

Glucose

Triacylglycerols, cholesterol

Potassium

Sodium

Folic acid

Milk, fat, pineapple juice Food, calcium, iron

Food

Food Food

Fruit juice or acid liquid Food

Food Food

Food

Food

Food

Pyridoxins

Food (milk)

Sodium

Potassium

Food

Glucose

Magnesium

Phosphorus

Potassium

Sodium

Food (milk)

Sodium

Potassium

Food (milk)

Decreased rate of absorption Enhanced CNS effect

Can cause hyperglycemia Decreased absorption of calcium and phosphorus; increased urinary excretion; chronic high dose can cause osteomalacia

Increased urinary nitrogen losses Increased urinary excretion and decreased serum levels Impairs glucose tolerance; increases plasma levels Increased serum levels Decreased excretion hyperkalemia Increased excretion hyponatremia Potential for folate deficiency Increased absorption Decreased absorption of dairy products and divalent and trivalent cations Increased absorption with high-fat meals and delayed gastric emptying

Increased absorption with high-fat meals and delayed gastric emptying Decreased rate and extent of absorption Didanosine unstable in acid Delayed absorption; adsorbent to highfiber high-pectin foods Slightly increased absorption Decreased rate of absorption; extent of absorption not affected Decreased absorption of food and milk

Increased absorption by delayed gastric emptying

Reduced absorption by delayed gastric emptying Reports of peripheral neuritis and paraesthesia Decreased total bioavailability of tolmetin;

decreased absorption of ibuprofen Hyponatremia (indomethacin/ketorolac) Hyperkalemia (indomethacin/ketorolac) Increased rate of absorption Hypoglycemia Hypomagnesemia Hypophosphatemia Hypokalemia Hyponatremia

Decreased total bioavailability of tolmetin Hyponatremia (indomethacin/ketorolac) Hyperkalemia (indomethacin/ketorolac) Decreased bioavailability of tolmetin; decreased absorption of ibuprofen

Table 2 Continued

Drug

Class

Food/nutrient

Effect/mechanism

Fluconazole Flucytosine

Foscarnet

Antifungal Antifungal

Antiviral

Furazolidone

Anti-infective

Furosemide Ganciclovir

Glipizide

Griseofluvin

Hydralazine Hydrochlorothiazide

HMG-CoA Reductase inhibitors Simvastatin Lovastatin Ibuprofen

Diuretic Antiviral

Antidiabetic

Antifungal

Diuretic Diuretic

Antihyperlipidemic

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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