O

Table 5 Important copper enzymes

Enzyme Source Function Cu/protein

Ascorbate oxidase Squash Ascorbate catabolism 8

Ceruloplasmin Plasma Iron oxidation 6-7

Cytochrome c oxidase Mitochondria Electron transport 2

Dopamine-ß-monooxygenase Adrenal Noradrenaline synthesis 8

Lysyl oxidase Aorta Collagen, elastin synthesis 1

Superoxide dismutase Erythrocyte Superoxide radical destruction 2

mean that copper is essential for the development of the microvascular system.

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