Protein Malabsorption

Protein-losing enteropathy (PLE) can also be treated with a variety of nutritional interventions. PLE due to dilated lymphatics, as with right heart failure, results in leakage of lymphocytes, proteins, and fats into the intestinal lumen. As with fat malabsorption, MCT-supplemented foods and formulas are indicated to allow improved fat absorption in PLE. Fat-soluble vitamin supplementation is indicated. In congenital protein malabsorption syndromes, peptide- or amino acid-based formulas are often helpful.

Mucosal disorders, including inflammatory bowel disease, allergic diseases, and celiac disease, are additional examples of disorders causing protein malabsorption. Once intestinal inflammation is reduced with appropriate medical or nutritional therapy, absorption of protein is usually improved. In Shigella infections, some studies have demonstrated improved nutritional outcomes with a high-protein diet during recovery from the acute symptoms of diarrhea.

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