R

Acylcarnitine transferase II

Carnitine

Acylcarnitine transferase I

Acyl carnitine

HS-CoA

Acyl-CoA

Figure 11 Carnitine-dependent transfer of fatty acyl groups. Two juxtaposed membrane transferase enzymes, acylcarnitine transferase I,II, are designed to transport a fatty acyl carnitine complex into the mitochondria and return the carnitine for additional reactions. Note that the acyl group is transferred to the carnitine from CoA and returned to CoA inside the mitochondria.

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