R12 R20

Semistarvation Refeeding

Figure 5 Pattern of changes in body weight, food intake, and adaptive thermogenesis during the various phases of the longitudinal 'Minnesota experiment' of human semistarvation and refeeding. The changes in adaptive thermogenesis at the various time points are assessed as changes in basal metabolic rate (BMR) after adjusting for changes in fat-free mass and fat mass and are expressed as a percentage of the baseline (control) BMR level. C, end of control (baseline) period; S12 and S24, week 12 and week 24 of semistarvation, respectively; R12 and R20, week 12 and week 20 after onset of refeeding, respectively. Data from Keys A, Brozek J, Henschel A, Mickelson O and Taylor HL (1950) The Biology of Human Starvation. Minneapolis: University of Minnesota Press; and Dulloo AG and Jacquet J (1998) Adaptive reduction in basal metabolic rate in response to food deprivation in humans: A role for feedback signals from fat stores. American Journal of Clinical Nutrition 68: 599-606.

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Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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