T1

Sphingomyelin VI Glucosylphosphatidylinositol-linked (rigid, uncharged) protein (GPI)

Figure 2 Topology of distribution of phospholipids within the plasma membrane of eukaryotic cells. The outer leaflet of the membrane bilayer is enriched in neutral PC and rigid components, such as sphingolipids and glucosylphosphatdylinositol-linked proteins. The distribution of charged acidic phospholipids, such as PS and PI, to the inner leaflet of the membrane is actively regulated by a combination of enzymes called flipases and scramblases.

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