Thrombosis and Fibrinolysis

The importance of thrombosis in causing heart disease is receiving increasing attention. Thrombosis, in contrast to atherosclerosis, is an acute event resulting in the formation of a thrombus or blood clot, which is an aggregate of fibrin, platelets, and red cells. Blood clotting or coagulation is an important process as it is responsible for repairing tissues after injury. Under normal physiological conditions, a blood clot forms at the site of injury. Platelets are attracted to the damaged tissue and adhere to the surface. They are then activated to release substances that attract more platelets, allowing platelet aggregation and triggering coagulation mechanisms.

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