Tissues

Biotin concentrations in plasma are small relative those of other water-soluble vitamins. Most biotin in plasma is free, dissolved in the aqueous phase of plasma. However, small amounts are reversibly bound and covalently bound to plasma protein (approximately 7 and 12%, respectively); binding to human serum albumin likely accounts for the reversible binding. Biotinidase has been proposed as a biotin binding protein or biotin carrier protein for the transport into cells. A biotin binding plasma glycoprotein has been observed in pregnant rats. Although the importance of protein binding in the transport of biotin from the intestine to the peripheral tissues is not clear, the immunoneutralization of this protein led to decreased transport of biotin to the fetus and early death of the embryo.

Low Carb Diets Explained

Low Carb Diets Explained

You can burn stored body fat for energy and shed excess weight by reducing the carbohydrate intake in your diet. Learn All About The Real Benefits of Low Carb Diets And Discover What They Can Really Do To Improve The Quality Of Your Life Today.

Get My Free Ebook


Post a comment