Type III or Familial Dysbetalipoproteinemia

In this disorder both plasma triacylglycerol and cholesterol are increased. Several mutations within the apo E gene locus have been found to be responsible for this disease; however, in most patients the complete expression of the clinical genotype needs additional interactions such as age, obesity, and diabetes. In addition to the accumulation in plasma of VLDL remnants and chylomicrons, other characteristics of this disorder are tuboeruptive xanthomas and in some cases also planar xanthomas. Therapies include diet and hypolipidemic agents such as fibrates, statin, or nicotinic acid. In most cases, diagnosis can be carried out first by agarose gel electrophoresis, followed by molecular biology techniques to detect the presence of the apo E-2 allele.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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