Vitamin D and Calcium

Chronic alcoholic patients are at increased risk for metabolic bone disease due to low vitamin D and hence decreased absorption of calcium. Alcoholic liver disease increases the likelihood of low circulating levels of 25-hydroxy vitamin D because of decreased excretion of bile required for absorption of this fat-soluble vitamin, poor diet, and often decreased sun exposure. Calcium deficiency results from low levels of vitamin D that are required to regulate its absorption, and also because the fat malabsorption that often accompanies alcoholic liver disease results in increased binding of calcium to unabsorbed intestinal fatty acids.

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